Anxiolytic/nonsedative agent-1

CAT: 0931-T23445-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T23445-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

355022-97-8

Target

GABA Receptor

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9861

Bioactivity

Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.

Smiles

C(C(N[C@H](C)C1=CC=CC=C1)=O)(=O)C=2C=3C(NC2)=CC=C(N(=O)=O)C3

Molecular Formula

C18H15N3O4

Molecular Weight

337.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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