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Antifolate agent 1

CAT: 0931-T212452-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T212452-01Size:10 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
518063-75-7
Target
Antifolate
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
Antifolateagent 1 (Compound 1) is an antifolate agent featuring a single-carbon bridge. It lacks RFC transport, shows no affinity for FR? and FR?, and exhibits no GARFTase inhibition activity. Antifolateagent 1 serves as a negative control in the development of folate receptor-targeted antifolate agents.
Smiles
O=C1C2=C(NC(CC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=C2)NC(N)=N1
Molecular Formula
C19H19N5O6
Molecular Weight
413.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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