TC-N 22A

• Target:

  GluR

• Related Pathways:

  Neuroscience

• Purity:

  0.9995

• Bioactivity:

  TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very low activity against mGlu 1, 2, 3, 5, and 7 receptors in excitation and forward allosteric models (EC50 >10 ?M) . TC-N 22A can be used in the study of central nervous system diseases.

• Smiles:

  N(C1=NC=2C=3C(=NNC3)CCCC2S1)C4=CC=CC=N4

• Molecular Formula:

  C14H13N5S

• Molecular Weight:

  283.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1314140-00-5