Cis-22a

• Target:

  Calcium Channel|||TRP/TRPV Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Metabolism

• Purity:

  0.9999

• Bioactivity:

  Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 ?M), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.

• Smiles:

  C(C(O)=O)(F)(F)F.CC=1C=C([C@H]2CC[C@H](CC2)N3CCN(CC3)C=4C=CC=NC4)C=CC1

• Molecular Formula:

  C24H30F3N3O2

• Molecular Weight:

  449.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1819366-84-1