TC-N 22A

CAT: 1410-M33939-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M33939-01Size:1 g
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Description
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very low activity against mGlu 1, 2, 3, 5, and 7 receptors in excitation and forward allosteric models (EC50 >10 μM) . TC-N 22A can be used in the study of central nervous system diseases.
CAS Number
1314140-00-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
283.35
Molecular Formula
C14H13N5S
Notes
Research use only, not for human use.
Receptor
GluR

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