Palbociclib-propargyl

CAT: 0931-T18515Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T18515Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2366269-23-8
Target
Others|||Ligands for Target Protein for PROTAC
Related Pathways
Others|||PROTAC
Bioactivity
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].
Smiles
CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC#C)CC3)nc2n(C2CCCC2)c1=O
Molecular Formula
C27H31N7O2
Molecular Weight
485.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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