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Palbociclib orotate

CAT: 0931-T72507-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T72507-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2757498-64-7
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell cycle arrest in cancer cells, applicable in research concerning HR-positive, HER2-negative breast cancer, and hepatocellular carcinoma [1] [3] [4].
Molecular Formula
C29H33N9O6
Molecular Weight
603.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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