Palbociclib orotate

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell cycle arrest in cancer cells, applicable in research concerning HR-positive, HER2-negative breast cancer, and hepatocellular carcinoma [1] [3] [4].

• Molecular Formula:

  C29H33N9O6

• Molecular Weight:

  603.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2757498-64-7