Palbociclib monohydrochloride

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  >99.99%

• Bioactivity:

  Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM) . It exhibits no inhibition against a panel of 36 additional protein kinases.

• Smiles:

  Cl.CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O

• Molecular Formula:

  C24H29N7O2·HCl

• Molecular Weight:

  483.99

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  827022-32-2