Lenalidomide-PEG3-iodine

CAT: 0931-T18068-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T18068-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||E3 Ligase Ligand-Linker Conjugate
Related Pathways
Others|||PROTAC
Bioactivity
Lenalidomide-PEG3-iodine, an E3 ligase ligand-linker conjugate, consists of a cereblon-based Lenalidomide ligand and a 3-unit polyethylene glycol (PEG) linker. This compound is utilized in creating various proteolysis targeting chimeras (PROTACs), including the highly effective PROTAC BTK degrader SJF620, which has a degradation concentration 50 (DC50) of 7.9 nM[1].
Smiles
O=C(N1)C(CCC1=O)N(C2=O)CC3=C2C=CC(OCCOCCOCCI)=C3
Molecular Formula
C19H23IN2O6
Molecular Weight
502.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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