Lenalidomide 4'-PEG3-amine (dihydrochloride)

Lenalidomide 4'-PEG3-amine (dihydrochloride)

• CAS Number: 2624336-87-2
• UNSPSC Description: Lenalidomide 4'-PEG3-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG3-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/lenalidomide-4-peg3-amine-dihydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCOCCOCCN)=CC=C3)=O)=O.Cl.Cl
• Molecular Weight: 507.41
• References & Citations: [1]Wang S, et al. Monofunctional intermediates for ligand-dependent target protein degradation. China, WO2017176958A1. 2017-10-12.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported