Palbociclib

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.999

• Bioactivity :

  Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-negative breast cancer.

• Smiles :

  O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCNCC4)N2)C5CCCC5

• Molecular Formula :

  C24H29N7O2

• Molecular Weight :

  447.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  571190-30-2