Palbociclib

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.999

• Bioactivity:

  Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-negative breast cancer.

• Smiles:

  O=C1N (C=2C (C (C) =C1C (C) =O) =CN=C (NC3=CC=C (C=N3) N4CCNCC4) N2) C5CCCC5

• Molecular Formula:

  C24H29N7O2

• Molecular Weight:

  447.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  571190-30-2