TIK-301

• Target:

  5-HT Receptor|||Melatonin Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience

• Bioactivity:

  TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively) . TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.

• Smiles:

  [C@@H](CNC(C)=O)(C)C=1C=2C(NC1)=CC(Cl)=C(OC)C2

• Molecular Formula:

  C14H17ClN2O2

• Molecular Weight:

  280.75

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  118702-11-7