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A011

CAT: 0931-T78711-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T78711-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ATM/ATR, Apoptosis
Related Pathways
Apoptosis, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Bioactivity
A011, a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor, exhibits an IC50 of 1.0 nM and triggers apoptosis as well as G2/M phase cell cycle arrest when combined with CPT-11, displaying notable antitumor activity [1].
Molecular Formula
C27H28N6O
Molecular Weight
452.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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