Products for Research Use Only

Ro 90-7501

CAT: 0931-T16773-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16773-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
293762-45-5
Target
ATM/ATR, Gamma-secretase, Beta Amyloid, Phosphatase, Apoptosis
Related Pathways
Apoptosis, Metabolism, Stem Cells, DNA Damage/DNA Repair, Proteases/Proteasome, Neuroscience, PI3K/Akt/mTOR signaling
Purity
0.998
Bioactivity
Ro 90-7501 is an amyloid β42 (Aβ42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV.
Smiles
NC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2
Molecular Formula
C20H16N6
Molecular Weight
340.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C