PTC-028

• Target :

  Apoptosis|||BMI-1

• Related Pathways :

  DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint

• Purity :

  0.9825

• Bioactivity :

  PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.

• Smiles :

  Cc1nc2cc(F)c(F)cc2n1-c1cncc(Nc2ccc(cc2)C(F)(F)F)n1

• Molecular Formula :

  C19H12F5N5

• Molecular Weight :

  405.32

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1782970-28-8