PTC-028

• Target:

  Apoptosis|||BMI-1

• Related Pathways:

  DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint

• Purity:

  0.9825

• Bioactivity:

  PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.

• Smiles:

  Cc1nc2cc (F) c (F) cc2n1-c1cncc (Nc2ccc (cc2) C (F) (F) F) n1

• Molecular Formula:

  C19H12F5N5

• Molecular Weight:

  405.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1782970-28-8