PTC-700

• Target:

  Microtubule Associated

• Related Pathways:

  Cytoskeletal Signaling

• Bioactivity:

  PTC-700 is an effective splicing modulator of microtubule-associated protein tau (MAPT) . It reduces 4R MAPT in P301L and S305N neurons with EC50 values of 1.3 to 1.8 nM and 0.5 to 2.6 nM, respectively.

• Smiles:

  N (CC1=NC=CS1) C2=C3C (C (C) =C (C[C@H] (C) N) S3) =NC (Cl) =C2

• Molecular Formula:

  C15H17ClN4S2

• Molecular Weight:

  352.91

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2476726-76-6