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MRS 1523

CAT: 0931-T16135-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16135-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
212329-37-8
Target
Calcium Channel, Adenosine Receptor, Others
Related Pathways
GPCR/G Protein, Metabolism, Neuroscience, Others, Membrane transporter/Ion channel
Bioactivity
MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 nM for human and rat A3 receptors, respectively) . In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively.
Smiles
CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c1ccccc1
Molecular Formula
C23H29NO3S
Molecular Weight
399.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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