MMAF sodium

• Target :

  ABC Transporter|||Microtubule Associated|||ADC Cytotoxin

• Related Pathways :

  Antibody-drug Conjugate/ADC Related|||Membrane transporter/Ion channel|||Cytoskeletal Signaling

• Bioactivity :

  MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.

• Smiles :

  [H][C@@]1([C@@H]([C@H](C(N[C@H](C([O-])=O)Cc2ccccc2)=O)C)OC)CCCN1C(C[C@H]([C@@H](N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C)[C@H](CC)C)OC)=O.[Na+]

• Molecular Formula :

  C39H64N5NaO8

• Molecular Weight :

  753.94

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1799706-65-2