MMAF sodium

CAT: 0931-T16122-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T16122-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1799706-65-2
Target
ABC Transporter|||Microtubule Associated|||ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related|||Membrane transporter/Ion channel|||Cytoskeletal Signaling
Bioactivity
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.
Smiles
[H][C@@]1([C@@H]([C@H](C(N[C@H](C([O-])=O)Cc2ccccc2)=O)C)OC)CCCN1C(C[C@H]([C@@H](N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C)[C@H](CC)C)OC)=O.[Na+]
Molecular Formula
C39H64N5NaO8
Molecular Weight
753.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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