MMAF-OtBu

• CAS Number :

  745017-95-2

• Target :

  Microtubule Associated|||ADC Cytotoxin

• Related Pathways :

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

• Purity :

  0.9894

• Bioactivity :

  MMAF-OtBu (Example 2) is an OtBu-modified MMAF for synthesising ADCs (antibody-drug conjugates) . MMAF is an antitumour microtubule polymerisation inhibitor commonly employed as the cytotoxic component in ADCs.

• Smiles :

  [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC(C)(C)C)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@H](C(C)C)NC)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

• Molecular Formula :

  C43H73N5O8

• Molecular Weight :

  788.07

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C