MMAF-OtBu

CAT: 0931-MF-0095471-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0095471-01Size:50 mg
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CAS Number
745017-95-2
Target
Microtubule Associated|||ADC Cytotoxin
Related Pathways
Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related
Purity
0.9894
Bioactivity
MMAF-OtBu (Example 2) is an OtBu-modified MMAF for synthesising ADCs (antibody-drug conjugates) . MMAF is an antitumour microtubule polymerisation inhibitor commonly employed as the cytotoxic component in ADCs.
Smiles
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(OC(C)(C)C)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@H](C(C)C)NC)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C43H73N5O8
Molecular Weight
788.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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BA2356-5MMAF-OtBu
B3270-10MMAF
MD067067-9OtBu-PEG9-OtBu
MD067067-8OtBu-PEG8-OtBu
MD067067-4OtBu-PEG4-OtBu
MD067067-1OtBu-PEG1-OtBu
MD067067-10OtBu-PEG10-OtBu
MD067067-5OtBu-PEG5-OtBu
MD067067-16OtBu-PEG16-OtBu
MD067067-3OtBu-PEG3-OtBu

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