MMAF-OtBu

• Target:

  Microtubule Associated|||ADC Cytotoxin

• Related Pathways:

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

• Purity:

  0.9894

• Bioactivity:

  MMAF-OtBu (Example 2) is an OtBu-modified MMAF for synthesising ADCs (antibody-drug conjugates) . MMAF is an antitumour microtubule polymerisation inhibitor commonly employed as the cytotoxic component in ADCs.

• Smiles:

  [C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (OC (C) (C) C) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@H] (C (C) C) NC) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]

• Molecular Formula:

  C43H73N5O8

• Molecular Weight:

  788.07

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  745017-95-2