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M-110

CAT: 0931-T15830-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T15830-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1395048-49-3
Target
Pim
Related Pathways
Chromatin/Epigenetic|||JAK/STAT signaling
Purity
0.9955
Bioactivity
M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases, showing a preference for PIM-3 (IC50=47 nM), and inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 ?M. M-110 also inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 ?M.
Smiles
CC\C(=N/NC(=O)c1ccnc(NCCCN2CCOCC2)c1)c1ccc(Cl)cc1O
Molecular Formula
C22H28ClN5O3
Molecular Weight
445.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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