Ribociclib succinate hydrate

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively) . It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.

• Smiles:

  O.OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1

• Molecular Formula:

  C27H38N8O6

• Molecular Weight:

  570.651

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1374639-79-8