FX-11

• Target:

  ROS|||Reactive Oxygen Species|||Dehydrogenase|||Apoptosis

• Related Pathways:

  Metabolism|||Apoptosis|||Immunology/Inflammation|||NF-?B

• Purity:

  0.9895

• Bioactivity:

  FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 ?M. FX-11 can activate PKM2 (pyruvate kinase M2) . FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

• Smiles:

  CCCc1c(O)c(O)c(C(O)=O)c2cc(Cc3ccccc3)c(C)cc12

• Molecular Formula:

  C22H22O4

• Molecular Weight:

  350.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  213971-34-7