FX-11

CAT: 0931-T15362-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T15362-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

213971-34-7

Target

ROS, Reactive Oxygen Species, Dehydrogenase, Apoptosis

Related Pathways

Metabolism, Apoptosis, Immunology/Inflammation, NF-κB

Purity

0.9895

Bioactivity

FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2) . FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor activity during xenotransplantation of lymphoma and pancreatic cancer.

Smiles

CCCc1c(O)c(O)c(C(O)=O)c2cc(Cc3ccccc3)c(C)cc12

Molecular Formula

C22H22O4

Molecular Weight

350.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-16214-01	FX-11
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A20900-10	FX-11 10mg
A20900-50	FX-11 50mg
A20900-5	FX-11 5mg
A20900-1	FX-11 1mg
A20900-10mM-D	FX-11 10mM * 1mL in DMSO
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FX-11

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