DS-437

• Target :

  Histone Methyltransferase|||Others

• Related Pathways :

  Chromatin/Epigenetic|||Others

• Bioactivity :

  DS-437 is a dual PRMT5/7 inhibitor with IC50 values of 6 ?M and also inhibits DNMT3A and DNMT3B with IC50 values of 52 ?M and 62 ?M, respectively. Additionally, DS-437 inhibits the methylation of FOXP3.

• Smiles :

  CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

• Molecular Formula :

  C15H23N7O4S

• Molecular Weight :

  397.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1674364-87-4