DS-437

CAT: 0931-T15169Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-T15169Size:2 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1674364-87-4

Target

Histone Methyltransferase, Others

Related Pathways

Chromatin/Epigenetic, Others

Bioactivity

DS-437 is a dual PRMT5/7 inhibitor with IC50 values of 6 μM and also inhibits DNMT3A and DNMT3B with IC50 values of 52 μM and 62 μM, respectively. Additionally, DS-437 inhibits the methylation of FOXP3.

Smiles

CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

Molecular Formula

C15H23N7O4S

Molecular Weight

397.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
BA4837-5.1	DS-437
A24360-5	DS-437 5mg
A24360-50	DS-437 50mg
A24360-10	DS-437 10mg
A24360-100	DS-437 100mg
B6785-5.1	CD 437
BA7172-1	HFI-437
MBS3603492-01	KNK-437
SIH-599-5MG	KNK 437

DS-437

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