CMS-121

• Target :

  Acetyl-CoA Carboxylase

• Related Pathways :

  Metabolism

• Purity :

  0.9948

• Bioactivity :

  CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM) . CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.

• Smiles :

  Oc1ccc(cc1O)-c1cc(OC2CCCC2)c2ccccc2n1

• Molecular Formula :

  C20H19NO3

• Molecular Weight :

  321.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1353224-53-9