CMS-121

• Target:

  Acetyl-CoA Carboxylase

• Related Pathways:

  Metabolism

• Purity:

  0.9948

• Bioactivity:

  CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM) . CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.

• Smiles:

  Oc1ccc (cc1O) -c1cc (OC2CCCC2) c2ccccc2n1

• Molecular Formula:

  C20H19NO3

• Molecular Weight:

  321.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1353224-53-9