AM-4668

• Target :

  GPCR

• Related Pathways :

  GPCR/G Protein|||Endocrinology/Hormones

• Purity :

  0.9992

• Bioactivity :

  AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, with a mouse brain/plasma ratio of only 0.02, and significantly reduced blood glucose levels in human GPR40 knock-in mice.

• Smiles :

  C(OC1=CC=C([C@H](CC(O)=O)C=2C=CON2)C=C1)C=3SC(=NC3C)C4=CC=C(C(F)(F)F)C=C4

• Molecular Formula :

  C24H19F3N2O4S

• Molecular Weight :

  488.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1011531-27-3