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0990CL

CAT: 0931-T13983-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T13983-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
511514-03-7
Target
CAMP, Others, Adrenergic Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Others
Purity
0.9912
Bioactivity
0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL could partially restore cAMP level, and high concentration of 0990CL (10μM) began to have negative effects on cell viability.
Smiles
N(C=1N=C(C2=C(N1)C=CC=C2)C3=CC=CC=C3)C=4NC(C)(C)C=C(C)N4
Molecular Formula
C21H21N5
Molecular Weight
343.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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