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0990CL

CAT: 0804-HY-102076-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-102076-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
0990CL is a specific heterotrimeric Gαi subunit inhibitor by direct interaction with Gαi. 0990CL is able to block α2AR mediated regulation of cAMP[1].
CAS Number
511514-03-7
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/0990cl.html
Purity
98.0
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC1(C)C=C(C)N=C(NC2=NC(C3=CC=CC=C3)=C4C=CC=CC4=N2)N1
Molecular Formula
C21H21N5
Molecular Weight
343.42
References & Citations
[1]Appleton KM, et al. Development of inhibitors of heterotrimeric Gαi subunits.Bioorg Med Chem. 2014 Jul 1;22 (13) :3423-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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