ERD-308

CAT: 0931-T13685-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T13685-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2320561-35-9

Target

PROTACs, Estrogen Receptor/ERR

Related Pathways

PROTAC, Endocrinology/Hormones

Bioactivity

ERD-308 induces >95% of ER degradation at concentrations as low as 5 nM in both cell lines (DC50 (concentration causing 50% of protein degradation) of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells, respectively) .ERD-308 is a highly potent PROTAC degrader of estrogen receptor (ER) for ER positive breast cancer treatment.

Smiles

C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCN(CCCCCOCC(N[C@H](C(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C[C@@H](O)C5)[C@](C)(C)C)=O)CC)C=C4

Molecular Formula

C55H65N5O9S2

Molecular Weight

1004.26

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
BA9215-5	ERD-308
VSD56135-01	ERD 308
A18446-100	ERD-308 100mg
A18446-50	ERD-308 50mg
A18446-25	ERD-308 25mg
A18446-10	ERD-308 10mg
A18446-5	ERD-308 5mg
MBS5820485	ERD-3111
HY-169367	ERD-1233
HY-164924	ERD-12310A

ERD-308

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