TAS-114

• Target:

  Others|||DNA/RNA Synthesis

• Related Pathways:

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Purity:

  0.9976

• Bioactivity:

  TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD) . TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.

• Smiles:

  C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCCC2)c1

• Molecular Formula:

  C21H29N3O6S

• Molecular Weight:

  451.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1198221-21-4