SPE39 rabbit pAb

CAT: 0855-ES12994-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES12994-01Size:50 µL

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Background

This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2) . Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]

Description

This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010],

UniProt

Q9H9C1

Swiss Prot

Q9H9C1

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human SPE39 AA range: 76-126

Target

SPE39

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasmic vesicle . Early endosome . Recycling endosome . Late endosome . Colocalizes in clusters with VPS33B at cytoplasmic organelles (PubMed:19109425) .

Gene ID (Human)

63894

UniProtKB · Q9H9C1

Spermatogenesis-defective protein 39 homolog

SPE39_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9H9C1
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: VIPAS39
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: hSPE-39
EC number: —
Processing: —
Secondary accessions: B4DPI6, O95434, Q9H7E1, Q9H9I9

Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoplasmic vesicleEndosome

Biological process

DifferentiationProtein transportSpermatogenesisTranscriptionTranscription regulationTransport

Disease

Disease variant

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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