S-methyl DM1

• Target:

  ADC Cytotoxin|||Microtubule Associated

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling

• Bioactivity:

  S-methyl DM1, a thiomethyl derivative of Maytansine, binds to tubulin (Kd of 0.93 ?M) and inhibits microtubule polymerization.

• Smiles:

  C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCSC) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]

• Molecular Formula:

  C36H50ClN3O10S

• Molecular Weight:

  752.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  912569-84-7