S-methyl DM1

CAT: 0931-T12805-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T12805-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

912569-84-7

Target

ADC Cytotoxin, Microtubule Associated

Related Pathways

Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling

Bioactivity

S-methyl DM1, a thiomethyl derivative of Maytansine, binds to tubulin (Kd of 0.93 μM) and inhibits microtubule polymerization.

Smiles

C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

Molecular Formula

C36H50ClN3O10S

Molecular Weight

752.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
OR310971	(S) - (+) -S-Methyl-S-phenylsulfoximine
EAA38125	S-Methyl-S-phenylsulfoximine
KTB52616-01	S-Cyclohexyl-S-methyl-sulfoximine
465013-01	S-Despropylamino S-Methyl Macitentan
OR88872-01	S-Methyl-S-2-naphthalenylsulfoximine
465007-01	S-Desethyl S-Methyl Amisulpride
463568-01	(R) - (-) -S-Methyl-S-phenylsulfoximine
OR310970-01	(R) - (-) -S-Methyl-S-phenylsulfoximine
OR78911-01	S-Methyl-S-4-pyridinylsulfoximine
HY-W004461-01	S-Methyl thiomethanesulfonate