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RORγ inverse agonist 2

CAT: 0931-T212030-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212030-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1242610-59-8
Target
ROR
Related Pathways
Metabolism
Bioactivity
RORγinverse agonist 2 (Compound 15) is a potent inverse agonist of the retinoic acid receptor-related orphan receptor RORγ, with IC50 values of 0.4 μM for Gal4-RORγ and 0.9 μM for full-length RORγ. This compound is useful for researching autoimmune diseases.
Smiles
C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C(=O)/C(=C\C6=CC=CO6)/C5)[H])[H])[H])([C@H](C(C)=C)CC2)[H]
Molecular Formula
C35H48O4
Molecular Weight
532.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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