NIC

• UNSPSC Description:

  NIC is a host invasion inhibitor. NIC can suppress host invasion by interacting with the major invasion-related protein, merozoite surface protein 1 (MSP-1). NIC prevents the invasion of Plasmodium falciparum and Plasmodium vivax into the host[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nic.html

• Smiles:

  O=CC1=C(N=C(CCCC)N1CC2=CC=C([N+]([O-])=O)C=C2)Cl

• Molecular Weight:

  321.76

• References & Citations:

  [1]Chandramohanadas R, et al. Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species. J Infect Dis. 2014 Nov 15;210(10):1616-26.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  114773-20-5