NIC

• Description :

  NIC is a host invasion inhibitor. NIC can suppress host invasion by interacting with the major invasion-related protein, merozoite surface protein 1 (MSP-1) . NIC prevents the invasion of Plasmodium falciparum and Plasmodium vivax into the host[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/nic.html

• Smiles :

  O=CC1=C(N=C(CCCC)N1CC2=CC=C([N+]([O-])=O)C=C2)Cl

• Molecular Formula :

  C15H16ClN3O3

• Molecular Weight :

  321.76

• References & Citations :

  [1]Chandramohanadas R, et al. Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species. J Infect Dis. 2014 Nov 15;210 (10) :1616-26.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [114773-20-5]