NPD-1335

CAT: 0931-T12250-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T12250-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2376326-31-5

Target

Parasite, Others, PDE

Related Pathways

Others, Metabolism, Microbiology/Virology

Bioactivity

NPD1335, a potent inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1), exhibits submicromolar activity against T. brucei parasites and an improved cytotoxicity profile. By elevating intracellular cAMP levels, NPD1335 disrupts the cell cycle, leading to cell death [1].

Smiles

[H][C@]12CC=CC[C@@]1([H])C(=NN(C(C)C)C2=O)c1ccc(OC)c(c1)C#CC(=O)NCc1ccccc1

Molecular Formula

C28H29N3O3

Molecular Weight

455.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-126250-01	NPD-1335
BA2129-5	NPD-001
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MBS5812309	NPD-008
GTR19211404-01	FTR-1335
HY-150025	(4aS,8aR) -NPD-001
QUECR-NPD-MS-IS	QuECHERS GC/NPD and LC/MS - EACH
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NPD-1335

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