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Mutated EGFR-IN-3

CAT: 0931-T12131-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T12131-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2375107-27-8
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
Mutated EGFR-IN-3 is a ATP-competitive and highly selective allosteric dibenzodiazepinone EGFR (L858R/T790M) and EGFR (L858R/T790M/C797S) inhibitor (IC50 of 12 nM and 13 nM, respectively.)
Smiles
O=C1C2=CC(OC3=CC=C(C=C3)N4CCN(C)CC4)=CC=C2NC5=CC=C(F)C=C5N1CC=6C=CC=CC6
Molecular Formula
C31H29FN4O2
Molecular Weight
508.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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