MK-7145

CAT: 0931-T12066-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T12066-02Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1255204-84-2

Target

Others, Potassium Channel

Related Pathways

Others, Membrane transporter/Ion channel

Bioactivity

MK-7145 is an inhibitor of ROMK (IC50 of 0.045 μM) .

Smiles

CC1=C2C(C(=O)OC2)=CC=C1[C@H](CN3CCN(C[C@H](O)C=4C(C)=C5C(=CC4)C(=O)OC5)CC3)O

Molecular Formula

C26H30N2O6

Molecular Weight

466.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Mk-7145

MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.

CAS Number	1255204-84-2
PubChem CID	59568713
IUPAC Name	5-[(1R)-1-hydroxy-2-[4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]piperazin-1-yl]ethyl]-4-methyl-3H-2-benzofuran-1-one
Molecular Formula	C26H30N2O6
Molecular Weight	466.5
XLogP	1.3
Topological Polar Surface Area	99.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Heavy Atom Count	34
Formal Charge	0
Complexity	694

SMILES

CC1=C(C=CC2=C1COC2=O)[C@H](CN3CCN(CC3)C[C@@H](C4=C(C5=C(C=C4)C(=O)OC5)C)O)O

InChI

InChI=1S/C26H30N2O6/c1-15-17(3-5-19-21(15)13-33-25(19)31)23(29)11-27-7-9-28(10-8-27)12-24(30)18-4-6-20-22(16(18)2)14-34-26(20)32/h3-6,23-24,29-30H,7-14H2,1-2H3/t23-,24-/m0/s1

InChIKey

OCKGFTQIICXDQW-ZEQRLZLVSA-N

Chemical Structure

2D Structure

CAS: 1255204-84-2

CID: 59568713

Formula: C26H30N2O6

MW: 466.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	466.5
XLogP3	1.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	466.21038668
Monoisotopic Mass	466.21038668
Topological Polar Surface Area	99.5 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	694
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
MBS3845463-01	MK-7145
A21030-10	MK-7145 10mg
A21030-50	MK-7145 50mg
A21030-25	MK-7145 25mg
A21030-5	MK-7145 5mg
A21030-100	MK-7145 100mg
A21030-1	MK-7145 1mg
2332458	WSE-7145 EzELISA TMB
324068-01	MK
167912	Midkine (MK, MK1, MK-1, MK 1) discontinued

MK-7145

Chemical Information

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