MK 0893

• Target:

  Glucagon Receptor

• Related Pathways:

  GPCR/G Protein

• Purity:

  0.9879

• Bioactivity:

  MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist (IC50=6.6 nM) with competitive, reversible, high binding affinity and functional cAMP activity, which attenuates glucagon induced blood glucose elevation and reduces ambient glucose levels in acute and chronic mouse models.

• Smiles:

  [C@@H](C)(N1C(=CC(=N1)C2=CC(Cl)=CC(Cl)=C2)C3=CC4=C(C=C3)C=C(OC)C=C4)C5=CC=C(C(NCCC(O)=O)=O)C=C5

• Molecular Formula:

  C32H27Cl2N3O4

• Molecular Weight:

  588.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  870823-12-4