MK 0893

CAT:
931-T12055
Size:
1 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
MK 0893 - image 1

MK 0893

  • Target :

    Glucagon Receptor
  • Related Pathways :

    GPCR/G Protein
  • Purity :

    0.9879
  • Bioactivity :

    MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist (IC50=6.6 nM) with competitive, reversible, high binding affinity and functional cAMP activity, which attenuates glucagon induced blood glucose elevation and reduces ambient glucose levels in acute and chronic mouse models.
  • Smiles :

    [C@@H](C)(N1C(=CC(=N1)C2=CC(Cl)=CC(Cl)=C2)C3=CC4=C(C=C3)C=C(OC)C=C4)C5=CC=C(C(NCCC(O)=O)=O)C=C5
  • Molecular Formula :

    C32H27Cl2N3O4
  • Molecular Weight :

    588.48
  • Shipping Conditions :

    Cool pack
  • Storage Temperature :

    -20°C
  • CAS Number :

    870823-12-4

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