MK 0893

CAT: 0931-T12055Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T12055Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
870823-12-4
Target
Glucagon Receptor
Related Pathways
GPCR/G Protein
Purity
0.9879
Bioactivity
MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist (IC50=6.6 nM) with competitive, reversible, high binding affinity and functional cAMP activity, which attenuates glucagon induced blood glucose elevation and reduces ambient glucose levels in acute and chronic mouse models.
Smiles
[C@@H](C)(N1C(=CC(=N1)C2=CC(Cl)=CC(Cl)=C2)C3=CC4=C(C=C3)C=C(OC)C=C4)C5=CC=C(C(NCCC(O)=O)=O)C=C5
Molecular Formula
C32H27Cl2N3O4
Molecular Weight
588.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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