MD-224

CAT: 0931-T11980-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T11980-01Size:1 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2136247-12-4
Target
Mdm2|||E1/E2/E3 Enzyme|||PROTACs|||MDM-2/p53
Related Pathways
Ubiquitination|||PROTAC|||Apoptosis
Purity
>99.99%
Bioactivity
MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) concept, and as a new class of anticancer agent.
Smiles
O=C1[C@@]2([C@]3(N[C@@H](C(NC4=CC=C(C(NCCCC#CC5=C6C(C(=O)N(C6)C7C(=O)NC(=O)CC7)=CC=C5)=O)C=C4)=O)[C@@H]2C8=C(F)C(Cl)=CC=C8)CCCCC3)C=9C(N1)=CC(Cl)=CC9
Molecular Formula
C48H43Cl2FN6O6
Molecular Weight
889.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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