MBM-55

• Target:

  Apoptosis|||Chk|||Akt|||GSK-3|||DYRK|||MAPK|||Aurora Kinase|||S6 Kinase|||CDK|||Bcr-Abl

• Related Pathways:

  Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Apoptosis|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling|||MAPK|||Stem Cells

• Purity:

  0.9998

• Bioactivity:

  MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

• Smiles:

  CN (C) CCn1cc (cn1) -c1ccn2c (cnc2c1) -c1ccc (C (N) =O) c (OCc2cccc (F) c2) c1

• Molecular Formula:

  C28H27FN6O2

• Molecular Weight:

  498.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2083622-09-5