LS-102

CAT: 0931-MF-0022810-01Size: 1 mgDry Ice: NoHazardous: No

CAT#:0931-MF-0022810-01Size:1 mg

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PRICE

AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

CAS Number

1456891-34-1

Target

Ligand for E3 Ligase|||E1/E2/E3 Enzyme

Related Pathways

Ubiquitination|||PROTAC

Purity

0.9892

Bioactivity

LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.

Smiles

CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1

Molecular Formula

C24H36N8O

Molecular Weight

452.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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LS-102

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