LS-102

• Target :

  Ligand for E3 Ligase|||E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination|||PROTAC

• Purity :

  0.9892

• Bioactivity :

  LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.

• Smiles :

  CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1

• Molecular Formula :

  C24H36N8O

• Molecular Weight :

  452.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1456891-34-1