Products for Research Use Only

JNJ-39758979

CAT: 0931-T11723L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11723L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1046447-90-8
Target
Histamine Receptor
Related Pathways
Immunology/Inflammation, Neuroscience, GPCR/G Protein
Purity
0.9962
Bioactivity
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively) . JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells.
Smiles
CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1
Molecular Formula
C11H19N5
Molecular Weight
221.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C