JNJ-5207787

• Target:

  Neuropeptide Y Receptor|||Others

• Related Pathways:

  Others|||Neuroscience|||GPCR/G Protein

• Bioactivity:

  JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 receptor and rat Y2 receptor, respectively.

• Smiles:

  N(C(/C=C/C1=CC(C#N)=CC=C1)=O)(C=2C=C3C(=CC2)CCN3C(C)=O)C4CCN(CCC5CCCC5)CC4

• Molecular Formula:

  C32H38N4O2

• Molecular Weight:

  510.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  683746-68-1