Oganomycin GB

• Description:

  Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  OC(CCCC(N[C@]1([C@]2([H])N(C(C(O)=O)=C(CS2)COC(/C=C/C3=CC=C(C=C3)O)=O)C1=O)OC)=O)=O

• Molecular Formula:

  C23H24N2O10S

• Molecular Weight:

  520.51

• References & Citations:

  [1]H Gushima, et al. Oganomycin A, a new cephamycin-type antibiotic produced by Streptomyces oganonensis and its derivatives, oganomycins B, GA and GB. J Antibiot (Tokyo) . 1981 Nov;34 (11) :1507-12.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  80458-10-2