Oganomycin GB

CAT: 0804-HY-N14926Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N14926Size:1 Each
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Description
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB[1].
CAS Number
[80458-10-2]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC(CCCC(N[C@]1([C@]2([H])N(C(C(O)=O)=C(CS2)COC(/C=C/C3=CC=C(C=C3)O)=O)C1=O)OC)=O)=O
Molecular Formula
C23H24N2O10S
Molecular Weight
520.51
References & Citations
[1]H Gushima, et al. Oganomycin A, a new cephamycin-type antibiotic produced by Streptomyces oganonensis and its derivatives, oganomycins B, GA and GB. J Antibiot (Tokyo) . 1981 Nov;34 (11) :1507-12.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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