γ-Secretase modulator 4

• Target:

  Others|||Gamma-secretase

• Related Pathways:

  Stem Cells|||Proteases/Proteasome|||Others|||Neuroscience

• Bioactivity:

  ?-Secretase modulator 4 is a potent ?-secretase modulator that reduces A?42 levels with IC50s of 0.017 ?M in mice and 0.014 ?M in humans.

• Smiles:

  CC1=C([C@H]2C=3N(C=C(N3)C4=CC=5C(N4)=CC=C(C#N)C5OC)CCO2)C=CC=C1F

• Molecular Formula:

  C23H19FN4O2

• Molecular Weight:

  402.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1420200-82-3