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γ-Secretase modulator 11 hydrochloride

CAT: 0931-T63638-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63638-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2434630-30-3
Target
Others, Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Others, Proteases/Proteasome
Bioactivity
γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM) . γ-Secretase modulator 11 hydrochloride significantly reduces brain Aβ42 levels and rescues the cognitive deficits exhibited by AD model mice. γ-Secretase modulator 11 hydrochloride has shown research potential in Alzheimer's disease.
Smiles
Cl.CNC(=O)c1ccc(cn1)-c1c(C)nc2c(OCc3ccc(cc3F)-c3ccc(F)cc3)cccn12
Molecular Formula
C28H23ClF2N4O2
Molecular Weight
520.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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