γ-Secretase modulator 11 hydrochloride

CAT: 0931-MF-0038597-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0038597-01Size:25 mg
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CAS Number
2434630-30-3
Target
Others|||Gamma-secretase
Related Pathways
Neuroscience|||Stem Cells|||Others|||Proteases/Proteasome
Bioactivity
?-Secretase modulator 11 hydrochloride is a potent, orally active ?-secretase modulator (IC50: 0.029 ?M) . ?-Secretase modulator 11 hydrochloride significantly reduces brain A?42 levels and rescues the cognitive deficits exhibited by AD model mice. ?-Secretase modulator 11 hydrochloride has shown research potential in Alzheimer's disease.
Smiles
Cl.CNC(=O)c1ccc(cn1)-c1c(C)nc2c(OCc3ccc(cc3F)-c3ccc(F)cc3)cccn12
Molecular Formula
C28H23ClF2N4O2
Molecular Weight
520.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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