EGFR-IN-11

CAT: 0931-T11158-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T11158-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2463200-44-2

Target

Apoptosis, EGFR

Related Pathways

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Purity

0.9993

Bioactivity

EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.

Smiles

CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n([C@@H]4CCN(C4)S(=O)(=O)C4CC4)c3n2)cc1

Molecular Formula

C29H35N9O2S

Molecular Weight

573.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
BA3176-5.1	EGFR-IN-11
GTR19235419-01	EGFR/HER2-IN-11
HY-168305	EGFR ligand-11
HY-161633-01	PROTAC EGFR degrader 11
sc-80543	EGFR (EGFR.1)
ant-042	EGFR

EGFR-IN-11

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