EGFR-IN-94

• Target:

  Apoptosis|||VEGFR|||EGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis|||JAK/STAT signaling

• Bioactivity:

  EGFR-IN-94 (compound 5a) is an EGFR inhibitor with an IC50 of 0.086 ?M. It exhibits IC50 values of 0.107 ?M for VEGFR-2 and 2.52 ?M for Topo II. In HepG-2 cells, EGFR-IN-94 induces apoptosis and causes cell cycle arrest at the S phase.

• Molecular Formula:

  C19H17ClN8OS

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C