Products for Research Use Only

EGFR-IN-94

CAT: 0931-T208752-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208752-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, VEGFR, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, JAK/STAT signaling
Bioactivity
EGFR-IN-94 (compound 5a) is an EGFR inhibitor with an IC50 of 0.086 μM. It exhibits IC50 values of 0.107 μM for VEGFR-2 and 2.52 μM for Topo II. In HepG-2 cells, EGFR-IN-94 induces apoptosis and causes cell cycle arrest at the S phase.
Molecular Formula
C19H17ClN8OS
Shipping Conditions
Ice Packs
Storage Temperature
-20°C