Products for Research Use Only
RegisterLogin

EGFR-IN-167

CAT: 0931-T211515-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T211515-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
3052761-67-5
Target
EGFR
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-1671 is a selective EGFR inhibitor with an IC50 value of 0.19 nM. It effectively inhibits various EGFR mutants, showing IC50 values of 0.109 nM for EGFR (L858R), 0.75 nM for EGFR (C797S), and less than 0.05 nM for EGFR (del19) . EGFR-IN-1671 covalently binds to the catalytically conserved lysine of EGFR in live mammalian cells. By inhibiting EGFR autophosphorylation, this compound demonstrates excellent antiproliferative activity. EGFR-IN-1671 is applicable in research on non-small cell lung cancer (NSCLC), glioblastoma, and various solid tumors.
Smiles
O=S(=O)(F)OC1=CC=CC(=C1)NC=2N=CN=C3C=C(OCCOC)C(OCCOC)=CC32
Molecular Formula
C20H22FN3O7S
Molecular Weight
467.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T9901A-1810-01AMG-167
T16021-01MBQ-167
T24202Jmv 167
T38750ABBV-167
T32337-01JWH-167
T205273-01JPHM-2-167
T85658-01Antibacterial agent 167
T86253-01Disperse red 167:1
T81883-01MAGE-3 Antigen (167-176) (human)
TMPY-01968-01CD32A Protein, Human, Recombinant (167 His, His)

Alternative Products

CatalogName
HY-176556EGFR-IN-167
BA3753-5MBQ-167
BA3349-5.1ABBV-167
GTR19163234-01OTS-167
HY-P1994JMV 167
GTR19174766-01ML-167

Popular Products