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DHODH-IN-4

CAT: 0931-T11027-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11027-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1148125-93-2
Target
DNA/RNA Synthesis, Parasite, Dehydrogenase
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Metabolism, Microbiology/Virology
Purity
0.9934
Bioactivity
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.
Smiles
ClC1=C(C2=CC(Cl)=C(NC(/C(=C(/C)\O)/C#N)=O)C=C2)C=CC=C1
Molecular Formula
C17H12Cl2N2O2
Molecular Weight
347.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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